DED and Squamous Metaplasia: A Close Interplay

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Dear Renukaprasad A R, Do you agree that IFN-γ modulates conjunctival epithelial squamous metaplasia caused by dry eyes? Dry eye is one of the most common medical diseases, affecting 7% to 20% of the adult population over the age of 40. Several components of the microenvironment contribute to the homeostasis of the ocular surface. Therefore, successful dry eye treatment should be aimed at restoring the homeostasis of the ocular surface microenvironment. Highlights: Relationship between DED and squamous metaplasia Mechanism of development of squamous metaplasia in DED Preclinical evidence for the role of IFN-γ in DED-induced conjunctival squamous metaplasia Click to Read If you don't want to receive these emails in the future, please unsubscribe.