Friday, August 11, 2023

Hyaluronic Acid for Dry Eye Disease: Does the Concentration Matter?

Dear Dr. Renukaprasad A R,
Do you recommend HA-containing eye drops to your dry eye disease (DED) patients?
Despite introducing new DED treatments, hyaluronic acid (HA) eye drops remain a vital treatment choice for tear supplementation in patients with mild to severe DED. HA, an anionic glycosaminoglycan mainly found in connective tissue, vitreous, and aqueous humor, coats the corneal endothelium. HA effectively binds water, avoids dehydration, is biocompatible, stabilizes the precorneal tear film, and increases ocular surface irregularity. As a result, HA is essential as a lubricant component in treating DED.
Check out this infographic to know more about the impact of the different concentrations of HA on DED.

Highlights:
  • Mechanism of action of HA in DED management
  • Pros and cons of HA-containing eye drops with a high concentration
  • Clinical efficacy of low and high concentration and combination of HA eye drops for DED
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