Thursday, December 22, 2022

Clinical Outcomes: Aqueous-Deficient and Evaporative Dry Eye

Dear Dr. Renukaprasad A R,
Are lipid-containing artificial tears appropriate to treat DED sub-types?

The predominant etiologies of DED are ADDE and EDE or a combination of them, with or without other etiological factors for DED. In addition, both ADDE and EDE sub-types affect tear homeostasis and worsen the patient's QoL. Hence, a multi-faceted management approach is needed early to prevent the vicious circle of DED.

Lipid-containing eye drops can significantly relieve DED symptoms by improving the lipid layer and its spreading ability. Therefore, they are appropriate for managing lipid-deficient EDE and improving the patient's QoL.
Check out this infographic on the proportion of patients categorized into the different cohorts of DED, including ADDE, EDE, and mixed.

Key highlights:
  • What is the distinction between ADEE and EDED?
  • Distribution of ADEE and EDED among patients
  • The tests and parameters used to categorize patients
  • Clinical evidence-based patient subtype classification
Abbreviations:
ADDE: Aqueous-deficient dry eye; DED: Dry eye disease; EDE: Evaporative dry eye; QoL: Quality of life.
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