Saturday, June 25, 2022

New Regulations for Surrogacy Clinics, and More

Hi Renukaprasad A R,
Docplexus News brings you the latest happenings in the field of medical science.              

Top Stories of This Week:
New Regulations for Surrogacy Clinics
New Treatment for Motor Neuron Disease
WHO Requests to Address Mental Health Issues
Algorithm Predicts Kidney Cancer Risk

This Week's Trending News JUST for You. Watch 'Docplexus Health Minute' from Monday to Friday and 'Health Minute Highlights' on Saturday & Sunday!

Disclaimer: The Health Minute intends to update the medical community about the latest happenings from around the world, including relevant decisions taken by policy-makers. We do not endorse any individual, community, or political party.
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Friday, June 24, 2022

Protect Ocular Surface with HPG Lubricants

Dear Doctor Renukaprasad A R,
Millions of people worldwide suffer from dry eye disease (DED), a multifactorial ocular condition causing a visual disturbance, discomfort, tear film instability, and damage to the ocular surface. The hydroxypropyl guar (HPG)-containing ocular lubricants are known to protect the ocular surface and improve DED signs and symptoms.
Read this "Journal Watch" summarizing a prospective, randomized, controlled study from the Journal of Ocular Pharmacology and Therapeutics, entitled 'Protecting the Ocular Surface and Improving the Quality of Life of Dry Eye Patients: A Study of the Efficacy of an HP-Guar Containing Ocular Lubricant in a Population of Dry Eye Patients.'
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Glaucoma: The Risk Factors (Part I)

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Hi Renukaprasad A R,
Glaucoma is optical neuropathy marked by the loss of retinal ganglion cells (RGCs), which results in characteristic optic nerve head (ONH) damage and recognizable visual field abnormalities. Although increased intraocular pressure (IOP) is regarded as the major risk factor, there is emerging evidence that vascular factors play a key role in glaucoma etiology. In addition, age, gender (women being at a higher risk than men), family history, race/ethnicity (African-American), descendants having a higher risk of developing glaucoma, and patients with near-sightedness are the general risk factors associated with glaucoma.
Systemic and ocular vascular factors are also linked with this condition. Some of the ocular risk factors include central corneal thickness (CCT), splinter/disc hemorrhage, retinal nerve fiber layer (RNFL), and cup-to-disc ratio.
Check out PART I of this post, which enumerates ocular risk factors and their role in glaucoma progression.
Click to Read
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Thursday, June 23, 2022

sSMBG in Early Diabetes: St. Carlos Study

Docplexus - Community of 380,000+ Doctors
Hi Renukaprasad A R,
Early and adequate therapy is one of the most effective ways to control type 2 diabetes mellitus (T2DM). However, patients must actively participate in self-monitoring of blood glucose (SMBG) to achieve glycemic objectives.
SMBG is significantly more beneficial in current T2DM therapy when performed in an organized manner. Structured SMBG (sSMBG) assists in attaining glycemic objectives, enables patients to meet dietary and physical activity goals, and assists healthcare practitioners (HCPs) in optimizing hypoglycemic treatments.
Check out this exclusive Journal Watch in the RocheDiabetes Infocenter, where two studies that demonstrate the relevance of sSMBG in the early treatment of diabetes have been discussed.

Reference: Gracia TR et al., World Journal of Diabetes. 2014 Aug 15;5(4):471
Read More
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A Crucial Role of IFN-γ in Squamous Metaplasia with Dry Eye Disease

Docplexus - Community of 380,000+ Doctors
Dear Renukaprasad A R,
Do you agree that IFN-y modulates conjunctival epithelial squamous metaplasia caused by dry eyes?
Dry eye is one of the most common medical diseases, affecting 7% to 20% of the adult population over the age of 40. Several components of the microenvironment contribute to the homeostasis of the ocular surface. Therefore, successful dry eye treatment should be aimed at restoring the homeostasis of the ocular surface microenvironment.
Highlights:
  • Relationship between DED and squamous metaplasia
  • Mechanism of development of squamous metaplasia in DED
  • Preclinical evidence for the role of IFN-γ in DED-induced conjunctival squamous metaplasia
View Infographic
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Wednesday, June 22, 2022

A Discussion on Hypertension and Diabetes

Hi Renukaprasad A R,
Hypertension is twice more prevalent in patients with diabetes than in those without diabetes. Also, patients with hypertension are often insulin resistant and are more susceptible to diabetes than healthy individuals. Therefore, clinicians must be thorough with the overlapping pathophysiology of these conditions for timely and effective treatment.
We bring you exclusive sessions by the experts, Dr. Abraham Oomam and Dr. Benny Negalur, TODAY, 6:00 PM IST onwards, where they will share their insights on diabetes, hypertension, and the underlying cardiovascular complications.
Session highlights:
  • Diabetes and HT : Pathophysiology, Risks and Complications
  • Management of Diabetes and HT
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Delving Deeper into Diabetic Neuropathy

Hi Renukaprasad A R,
  • Type 2 diabetes mellitus has been on the rise in India; its prevalence has increased from 7.1% in 2009 to 8.9% in 2019.
  • Diabetic neuropathy is a serious complication in diabetic patients. Among its diverse forms, diabetic peripheral neuropathy , commonly affecting feet, legs, arms, and hands, has a high prevalence of 18.8 to 61.9% in India.
  • Alcoholic neuropathy resulting from excessive consumption of alcohol and toxic neuropathy resulting from exposure to toxins are neuropathies that are not caused by diabetes.
  • Watch this video, where Prof. (Dr.) Satish Khadilkar and Dr. Manilka Sumanatilleke discuss various issues related to diabetic neuropathy, including the clinical presentation, investigation, and treatment, along with a brief discussion on alcoholic and toxic neuropathy.
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How Does Meibomian Gland Dysfunction Cause DED ?

Hi Renukaprasad A R,
The meibomian glands are the lipid secreting glands in the eyelids that maintain tear film stability. Corneal disorders, eyelid inflammation, and microbial growth are significant causes of meibomian gland dysfunction (MGD), which ultimately causes dry eye disease (DED) among individuals. This vicious circle gives an idea of the pathogenic mechanism that connects both MGD and DED.
Here is an article that gives an overview of the new pathophysiological scheme for MGD to identify the pathological mechanisms of DED better.
Highlights:
  • An overview of MGD and its classification
  • A synopsis of MGD pathophysiology
  • The vicious cycle in DED
  • The targeted therapeutic approaches for DED
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